Julia Roberts, Coldplay, Jennifer Aniston, Julianne Moore, Jodie Foster join NBC's 'Red Nose Day'

Hollywood's biggest stars continue to line up to have fun, raise money and change lives on "Red Nose Day," a three-hour live entertainment event airing Thursday, May 21 (8-11 p.m. ET), on NBC. Featuring comedy, videos produced by Funny Or Die, music performances and Hollywood's favorite stars, the benefit event will help 12 charity organizations lift children and young people out of poverty, in the U.S. and throughout the world.

Julia Roberts, Coldplay, Jennifer Aniston, Julianne Moore, Jodie Foster, Reese Witherspoon and Neil Patrick Harris will appear, along with Sienna Miller, Paul Rudd, Olivia Wilde, Eddie Redmayne, Benedict Cumberbatch, Sir Ian McKellen, Orlando Bloom, Leslie Mann, January Jones and Simon Cowell. Also slated to appear are Naomi Campbell, Anna Camp, Jeanne Tripplehorn, Yvette Nicole Brown, Retta, Natalie Morales, Danny Pudi and Rob Huebel.

The star-studded event for charity also will feature "Game of Thrones" cast members Kit Harington, Peter Dinklage, Nikolaj Coster-Waldau, Emilia Clarke, Iwan Rheon, Thomas Brodie-Sangster, Mark Addy, John Bradley, Rose Leslie, Alfie Allen and Charlotte Hope. "Orange is the New Black" cast Dascha Polanco, Samira Wiley, Yael Stone, Selenis Leyva, Lea DeLaria, Adrienne C. Moore and Jackie Cruz also will be part of the fun-raising special.

An enormously popular annual event in the U.K. that has raised more than $1 billion over the past 30 years, "Red Nose Day" is coming to America for the first time ever. People from all walks of life are encouraged to have fun and raise money through buying red noses (sold exclusively at Walgreens and Duane Reade stores nationwide), organizing fundraising events and watching and donating during the television special.

For more information, visit www.rednosedayusa.com.

The event will feature sketch comedy, parodies, live musical performances and short appeals films that shed light on those in need. Previously announced stars include Will Ferrell, Jack Black, John Krasinski, Emily Blunt, Michelle Rodriguez, Gwyneth Paltrow, Sam Smith, John Legend and "Voice" coaches Adam Levine, Blake Shelton, Christina Aguilera and Pharrell Williams, along with Matt Lauer, Carson Daly, Bill and Melinda Gates, Nick Offerman, Elizabeth Banks, Chris Pine, Jeff Goldblum, Billy Eichner, Martin Short, Laura Linney, Anna Kendrick, Sean "P. Diddy" Combs, John Michael Higgins and Stephen Merchant.