Grammy-winning musical artist and actress Janet Jackson will join George Lopez for opening night as "Lopez Tonight" kicks off its second season in a new timeslot. Oscar-winning actor Jamie Foxx; two-time Oscar winner Denzel Washington; Howie Mandel; Hilary Duff; "Glee" star Jayma Mays; comedian Russell Peters; rapper DMX; and online sensation Antoine Dodson are also set to appear during the show's premiere week.  The new season of "Lopez Tonight" will launch Monday, Nov. 8, at midnight (ET/PT), following the premiere of "Conan" on TBS.

The following is a schedule for the opening week of "Lopez Tonight's" second season:

• Monday, Nov. 8 - Janet Jackson and Antoine Dodson
• Tuesday, Nov. 9 - Jamie Foxx and Jayma Mays
• Wednesday, Nov. 10 - Howie Mandel and musical guest DMX
• Thursday, Nov. 11 - Denzel Washington, Hilary Duff and comedian Russell Peters

"Lopez Tonight" offers a new spin to late-night comedy with George's signature everyman comedy.  Now at midnight, George anchors the second half of television's most exciting late-night lineup.  Each night's hour will feature George's standout standup, chats with celebrity guests, live music and memorable comedy bits.  Since premiering in November 2009, "Lopez Tonight" has delivered one of late-night television's most diverse audiences.

Lopez and Robert Morton serve as the executive producers for the series, which is produced for TBS by 2.2 Productions, paraMedia Inc., Panamort Television and Telepictures Productions.